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While no model fully recapitulates dry AMD, these two acute in vitro models effectively capture several key features observed in the RPE during the progression of AMD, thereby establishing a relevant platform for evaluating potential therapies for AMD and GA

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709 Mitochondria play a critical role in aerobic oxidation, converting various forms of cellular energy into ATP, which is essential for sustaining the metabolic needs of cancer cells

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Oveporexton: Oveporexton (TAK-861) is a small molecule orexin receptor 2 (OX2R) selective agonist that restores orexin signaling to address the underlying orexin neuron loss in narcolepsy type 1

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